Related Experiment Videos
Double-blind, placebo-controlled lithium treatment in chemotherapy induced aplasia for AML: reduced antibiotic
S Collado1, D Charron, L Degos
1Hôpital Saint Louis, Unite Fonctionnelle D'Hematologie, Paris, France.
Medical Oncology and Tumor Pharmacotherapy
|January 1, 1988
Abstract:
A double-blind placebo-controlled study on lithium (Li) therapy after chemotherapy-induced bone marrow aplasia was undertaken in 53 patients with acute myeloblastic leukemia (AML). No difference was observed between the two groups for the duration of aplasia, the number of units of platelets or RBC transfused, the complete remission rate or the disease free survival. However, a statistically significant reduction in the number of days of antibiotic therapy required was found in the treated group (10.55 +/- 2.72 vs 12.73 +/- 3.60, P less than 0.05).