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A direct and selective electrochemical hydrogen sulfide sensor.

Micah D Brown1, Jackson R Hall1, Mark H Schoenfisch1

  • 1Department of Chemistry, University of North Carolina at Chapel Hill, CB 3290, Chapel Hill, NC, 27599, United States.

Analytica Chimica Acta
|November 21, 2018
PubMed
Summary

This study introduces a novel surface preconditioning method for electrochemical hydrogen sulfide (H2S) detection. The optimized electrode maintains sensitivity in biological samples, overcoming sulfur passivation issues.

Keywords:
Anti-biofoulingElectropolymerized filmHydrogen sulfidePhenylenediamineSulfur poisoningSurface conditioning

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Area of Science:

  • Electrochemistry
  • Biosensing
  • Analytical Chemistry

Background:

  • Direct amperometry for hydrogen sulfide (H2S) detection is hindered by elemental sulfur byproduct formation, which passivates electrodes.
  • This passivation leads to reduced sensitivity and performance variability in biological samples.

Purpose of the Study:

  • To develop and evaluate a surface preconditioning strategy for glassy carbon electrodes to mitigate sulfur passivation during H2S detection.
  • To investigate the H2S permselective behavior of electropolymerized films and their anti-biofouling properties in biological media.

Main Methods:

  • A surface preconditioning procedure was employed to deposit elemental sulfur on glassy carbon electrodes prior to H2S measurement.
  • Electropolymerized films were developed and characterized for H2S selectivity against biological interferents.
  • The modified electrodes were tested for anti-biofouling capabilities in simulated wound fluid.

Main Results:

  • The preconditioning method effectively managed sulfur deposition on the electrode surface.
  • Electropolymerized films demonstrated H2S permselectivity and anti-biofouling properties.
  • The optimized electrode achieved a low detection limit (<100 nM) and retained ~80% sensitivity in proteinaceous media.

Conclusions:

  • Surface preconditioning of electrodes is a viable strategy to overcome passivation issues in H2S electrochemical detection.
  • Electropolymerized films offer a promising approach for selective and stable H2S sensing in complex biological environments.