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[Prevalence and characteristics of chronic obstructive pulmonary disease in non-smokers]
Josep Montserrat-Capdevila1, Pere Godoy2, Josep Ramon Marsal3
1Consultorio Local de Bellvís, ABS Pla d'Urgell, Atención Primaria, Institut Català de la Salut, Bellvís, Lleida, España; Institut de Recerca Biomèdica (IRB) de Lleida, Lleida, España; Agència de Salut Pública de Catalunya, Departament de Salut, Lleida, España; Facultat de Medicina, Universitat de Lleida, Lleida, España.
Objective:
The objective of the study was to know the profile of patients diagnosed with chronic obstructive pulmonary disease (COPD) and who have never been smokers.
Design:
A transversal study.
Location:
Primary Care Centre of Pla d'Urgell (Primary care setting in Lleida, Spain).
Participants:
512 patients older than 40 years with COPD from Primary Care Centre of Pla d'Urgell with a compatible spirometry [forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) ratio <0.7) to the beginning of the study.
Main Measurements:
The dependent variable was de COPD in non-smokers and the independents were variables collected from the information on the respiratory clinical history, the risk factors of the patients and on quality of life. We designed a predictor model of COPD in non-smokers compared to smokers.
Results:
33.2% of COPD patients had never been smokers, 59.4% of whom were women. The average FEV1 for non-smokers was 70.5 (SD=17.1), higher than 62.6 (SD=18.5) for smokers/former smokers (p<0.001). The coverage of pneumococcal vaccination 23V was better in non-smokers (75.3%), p<0.001. COPD in non-smokers (compared to smokers/former smokers) were: mostly women (OR=16.46), older (OR=1.1), with better FEV1 (OR=1.1), better perception of quality, EuroQoL-5D (OR=0.8), with lower prevalence of diabetes (OR=0.5), lower level of studies (OR=0.2), and with fewer previous hospitalizations (OR=0.3).
Conclusions:
The study evidences a high proportion of non-smokers in COPD patients. Our study aims that older women with less severity would be associated with an increased risk of COPD in non-smokers. It seems to indicate that COPD in non-smokers would appear at later ages and would be milder than smoking-related COPD.
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