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The Headache and Neck Pain in Ischemic Stroke Patients Caused by Cervicocerebral Artery Dissection. A Case-Control
Yuhan Wang1, Wenchao Cheng1, Yajun Lian1
1Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province, People's Republic of China.
Insights
Headache and neck pain in ischemic stroke patients may indicate cervicocerebral artery dissection (CAD), often presenting as severe, throbbing pain. Anterior circulation dissection typically causes temporal pain, while posterior circulation dissection is linked to occipital and neck pain.
Area of Science:
- Neurology
- Vascular Medicine
- Pain Management
Background:
- Headache and neck pain are common symptoms in patients experiencing cervicocerebral artery dissection (CAD).
- Differentiating the cause of these symptoms is crucial for effective treatment of ischemic stroke.
Purpose of the Study:
- To identify characteristics of headache and neck pain that can help screen for CAD in ischemic stroke patients.
- To compare pain patterns between CAD and large artery atherosclerosis (LAA) in ischemic stroke.
Main Methods:
- Prospective observation of 81 ischemic stroke patients with CAD and 84 with LAA.
- Analysis of headache and neck pain characteristics in relation to stroke etiology.
- Categorization of pain based on location, type, and severity.
Main Results:
- CAD patients more frequently reported severe pain (46.9%) compared to LAA patients (11.8%).
- Throbbing pain was more prevalent in CAD (30.0%) versus LAA (43.8% pulsating).
- Anterior circulation dissection correlated with temporal pain; posterior circulation dissection with occipital/neck pain.
Conclusions:
- Ischemic stroke patients with CAD often experience severe, throbbing headache and neck pain.
- Pain location can indicate the affected artery's circulation (anterior vs. posterior).
- Pain characteristics serve as valuable indicators for screening CAD in stroke patients.
Background And Purpose:
The symptom of headache and neck pain is common in patients with cervicocerebral artery dissection (CAD). We attempt to screen ischemic stroke patients with CAD based on the characteristics of the pain.
Methods:
Eighty-one consecutive ischemic stroke patients with CAD from 2010 to 2017 and 84 consecutive ischemic stroke patients with large artery atherosclerosis (LAA) were registered prospectively and observed in Zhengzhou, China. Those ischemic stroke patients complained of headache and neck pain were categorized into 2 groups. By analyzing the difference of headache and neck pain in 2 groups, we summarized characteristics of the pain secondary to CAD.
Results:
There were 34 patients in CAD group and 19 patients in LAA group. As for patients in CAD group, the pain could be located in the ipsilateral (41.9%), bilateral (41.9%), or contralateral (16.1%) side of the dissected artery, but in LAA group the pain was often in both sides (68.4%). When the dissected artery was involved in anterior circulation, 55.6% of CAD patients had pain in temporal and when involved in posterior circulation, 65.2% of CAD patients had pain in the occipital and neck. Patients with CAD had a higher prevalence of throbbing pain (30.0%), while pulsating pain (43.8%) was more common in LAA group. Patients often presented with severe pain (46.9%) in CAD group, while less frequently (11.8%) in LAA group, with a significant difference (P = .003). And there was a significant difference between the length (≥20 mm) of the involved artery and severity of the pain (P = .028) in CAD group.
Conclusions:
Ischemic stroke patients caused by CAD tend to suffer from headache and neck pain, which may be severe and throbbing, compared with those resulting from LAA. The anterior circulation dissection has a higher prevalence of temporal pain while posterior circulation dissection is typically more associated with occipital and neck pain.
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