Related Experiment Video
Updated: Feb 2, 2026

Implantation of Human-Sized Coronary Stents into Rat Abdominal Aorta Using a Trans-Femoral Access
Published on: November 19, 2020
Access and closure management of large bore femoral arterial access
Amir Kaki1, Nimrod Blank1, M Chadi Alraies1
1Wayne State University, School of Medicine, Detroit Medical Center, Detroit Heart Hospital, Detroit, Michigan.
Insights
Large-bore arterial access for cardiac catheterization can be safe and effective. Implementing a specific protocol for femoral artery access and sheath management minimizes vascular complications.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Vascular Access Techniques
Background:
- Femoral and radial artery access are standard for percutaneous coronary interventions.
- Despite technological advancements, bleeding and vascular complications remain significant, particularly with large-bore access.
- Effective hemostasis techniques for large-bore arterial access are not well-documented.
Purpose of the Study:
- To describe a protocol for large-bore femoral artery sheath insertion and management.
- To highlight techniques for safe vascular access and effective hemostasis in high-volume interventional procedures.
Main Methods:
- Detailed description of a protocol for femoral artery large-bore sheath insertion.
- Includes site identification, device selection, insertion, limb perfusion assessment during mechanical circulatory support (MCS), and hemostasis.
- Protocol implemented at a high-volume tertiary care center.
Main Results:
- Large-bore femoral artery access is feasible and safe when a protocol is followed.
- Associated with low complication rates, even in complex procedures with prolonged MCS support.
- Specific techniques ensure effective hemostasis post-sheath removal.
Conclusions:
- A structured protocol for large-bore femoral artery access and sheath management leads to safe procedures.
- This approach effectively minimizes vascular complications in interventional cardiology.
- The described techniques are crucial for centers performing high-volume endovascular and structural heart interventions.
Abstract:
Femoral and radial artery access continue to be the standard of care for percutaneous coronary interventions. Cardiac catheterization has progressed to encompass a wide range of diagnostic and interventional procedures including coronary, peripheral, endovascular, and structural heart disease interventions. Despite advanced technology to make these procedures safe, bleeding, and vascular complications continue to be a substantial source of morbidity, especially in patients undergoing large-bore access procedures. New variations of percutaneous devices have reduced complications associated with these procedures. However, safe vascular access with effective hemostasis requires special techniques which have not been well described in the literature. Large-bore femoral artery access is feasible, safe, and associated with low complication rates when a protocol is implemented. Wayne State University, Detroit Medical Center Heart Hospital is a tertiary care, high-volume center for endovascular, structural heart and complex high risk indicated procedures with more 150 procedures involving mechanical circulatory support (MCS) devices per year. In this manuscript, we describe our approach to femoral artery large-bore sheath insertion and management. Our protocol includes proper identification of the puncture site, device selection, insertion, assessment of limb perfusion while on prolong MCS support, and hemostasis techniques after sheath removal.
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Peripheral Artery Disease IV: Nursing Management
Angle Closure Glaucoma: Treatment
Tonsillitis II: Management
Impression Management Techniques I: Managing Appearances
Arteries of Lower Limbs

