Myeloperoxidase activity and acute coronary syndrome survival: long-term evaluation in the ERICO study
Alessandra Vl Quidim1, Tatiana C Bruno1, Paola Caroline Lacerda Leocádio2
1Center for Clinical & Epidemiological Research, Internal Medicine Department, Hospital Universitário, Universidade de Sao Paulo, Brazil.
Aim:
We aimed to analyze the influence of myeloperoxidase (MPO) activity on mortality in the Acute Coronary Syndrome Registry Strategy (ERICO) study.
Methods:
MPO activity levels were evaluated in 342 patients. We performed survival analyses using Kaplan-Meier curves and Cox regression with respective hazard ratios, 95% CI, according to MPO tertiles distribution up to 7 years of follow-up.
Results:
Higher MPO activity levels were seen in men, smokers, diabetics and those who were taking aspirin. MPO activity levels were neither significant in relation to mortality nor to survival rates up to seven years.
Conclusion:
We found no relationship between elevated levels of MPO activity post-acute coronary syndrome and mortality up to 7-years of follow-up in the ERICO study.
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