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Updated: Feb 2, 2026

Author Spotlight: Metallic Nanocomposites to Eliminate Antibiotic-Resistant Bacteria
Published on: October 4, 2024
Powerful antibacterial activity of graphene/nanoflower-like nickelous hydroxide nanocomposites
Na Li1, Chujie Zeng1, Qipin Qin1
1Guangxi Key Laboratory of Agricultural Resources Chemistry & Biotechnology, College of Chemistry & Food Science, Yulin Normal University, 1303 Jiaoyudong Road, Yulin, 537000, PR China.
Aim:
The development of new and efficient antibacterial agents is urgent to overcome emerging antimicrobial resistance.
Materials & Methods:
Herein, we have presented a new type of 3D antibacterial system to prompt bacteria to contact with the any plane of nanocomposites.
Results:
Comparing the antibacterial activity of graphene oxide, reduced graphene oxide and graphene-loaded nanoflower-like nickelous hydroxide (GN/Ni(OH)2) nanocomposites; the GN/Ni(OH)2 showed stronger bactericidal capability toward Gram-negative/-positive bacteria. Moreover, the GN/Ni(OH)2 with low cytotoxicity can promote it as 'green' antimicrobial agents. And, the GN/Ni(OH)2 presented long-term stable antibacterial effectiveness after 2-month storage. The antibacterial mechanisms of GN/Ni(OH)2 were evidenced as the 3D contact and violent damage to the bacterial structure.
Conclusion:
The GN/Ni(OH)2 provides new insights into the antibacterial properties of 3D nanocomposites for effectively fighting pathogen threats in biomedicine and public health.
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