Fabrication of injectable CuS nanocomposite hydrogels based on UCST-type polysaccharides for NIR-triggered
Yueyuan Zheng1, Yuqing Liang, Depan Zhang
1College of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan Province 410083, P. R. China. juanli@csu.edu.cn xiaoyisun@csu.edu.cn.
Abstract:
Injectable nanocomposite hydrogels containing small copper sulfide nanoparticles (6-8 nm) with a 54.6% photothermal conversion efficiency have been facilely prepared by applying an upper critical solution temperature (UCST)-type biopolymer gellan. This minimally invasive formulation ablates cancer completely in vivo after NIR-triggered chemo-photothermal therapy.
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