Related Experiment Video

Updated: Feb 2, 2026

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
08:45

Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes

Published on: May 10, 2022

2.4K

Is there an association between vitamin D level and iron deficiency in children?

Meriç Kaymak Cihan1,2, Elif Ünver Korğalı3

  • 1Division of Pediatric Hematology and Oncology, Department of Pediatrics, Cumhuriyet University Faculty of Medicine, Sivas, Turkey.

Archivos Argentinos De Pediatria
|November 21, 2018
PubMed

Insights

Maternal and child vitamin D (VitD) deficiency is linked to iron deficiency and anemia (IDA) in young children. Ensuring adequate VitD levels in mothers and children is crucial for preventing pediatric IDA.

Area of Science:

  • Pediatric Hematology
  • Nutritional Science
  • Public Health

Background:

  • Vitamin D plays a role in erythropoiesis, the process of red blood cell formation.
  • Iron deficiency anemia (IDA) is a prevalent nutritional disorder in young children globally.
  • Understanding the interplay between vitamin D and iron status is essential for effective prevention strategies.

Purpose of the Study:

  • To investigate the association between maternal and child 25-hydroxyvitamin D (25-OHD) levels and the prevalence of iron deficiency (ID) and IDA.
  • To identify risk factors for IDA in children aged 6 months to 5 years, considering both vitamin D and iron status.

Main Methods:

  • A cross-sectional study involving 117 children aged 6 months to 5 years and their mothers.
  • Measurements included complete blood count, serum iron, total iron-binding capacity, ferritin, and 25-OHD levels.
  • Data on infant and maternal supplementation, breastfeeding, and medical history were collected.

Main Results:

  • Children and mothers in the iron deficiency/anemia group exhibited significantly higher rates of vitamin D deficiency compared to the control group.
  • Lower maternal 25-OHD levels were identified as an independent risk factor for IDA in children.
  • Positive correlation observed between hemoglobin levels and maternal/child 25-OHD.

Conclusions:

  • Maternal and child vitamin D deficiency is significantly associated with iron deficiency and anemia in children aged 6 months to 5 years.
  • This highlights the importance of monitoring and ensuring adequate vitamin D status in both mothers and young children to prevent pediatric IDA.
Abstract

Keywords:
ChildIron deficiencyVitamin D

More Related Videos

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay05:08

Measurement of Tissue Non-Heme Iron Content using a Bathophenanthroline-Based Colorimetric Assay

Published on: January 31, 2022

5.6K
Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children07:36

Classical Short-Delay Eyeblink Conditioning in One-Year-Old Children

Published on: September 1, 2018

40.3K

Related Concept Videos

Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
2.5K
Association Areas of the Cortex01:21

Association Areas of the Cortex

Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
9.4K
Associative Learning01:27

Associative Learning

Associative learning is a fundamental concept in behavioral psychology, wherein a connection is established between two stimuli or events, leading to a learned response. This process is critical in understanding how behaviors are acquired and modified. Conditioning, the mechanism through which associations are formed, can be divided into two main types: classical conditioning and operant conditioning, each elucidating different aspects of associative learning.
Classical conditioning, also known...
1.3K
Leveling Effect01:29

Leveling Effect

In acid-base chemistry, the leveling effect refers to the limitation imposed by the solvent on the strength of acids and bases in solution. When a base stronger than the solvent's conjugate base is used, it deprotonates the solvent until the base is entirely consumed, making it ineffective against weaker acids. Conversely, an acid stronger than the solvent's conjugate acid protonates the solvent until the acid is depleted, rendering it ineffective against weaker bases. Essentially, the...
1.4K
Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
7.9K
Mineral, Vitamin and Water Absorption01:27

Mineral, Vitamin and Water Absorption

Electrolytes are essential minerals and ions primarily obtained from the diet and absorbed through the gastrointestinal tract. Most electrolytes are absorbed in the small intestine. While the absorption of iron and calcium primarily occurs in the duodenum, calcium is also absorbed in the jejunum and ileum. In these regions, passive diffusion contributes to its absorption alongside active transport mechanisms in the duodenum. These ions can exit the enterocytes through specialized active...
1.6K