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Reversible dilated cardiomyopathy as a complication of adrenal cortex insufficiency: a case report

Mohammad Alkhateeb1, Mohammad Alsakkal2, Mohammad Nour Alfauri2

  • 1Damascus University - Faculty of Medicine, Damascus, Syria. moh-alkh-123@hotmail.com.

Journal of Medical Case Reports
|November 22, 2018
PubMed

Insights

Addison's disease can lead to dilated cardiomyopathy in children. Glucocorticoid therapy effectively reversed cardiac dysfunction in a pediatric case, highlighting a rare but treatable complication of primary adrenal insufficiency.

Area of Science:

  • Pediatric Cardiology
  • Endocrinology
  • Rare Diseases

Background:

  • Cardiovascular complications are known in Addison's disease.
  • Primary adrenal insufficiency (Addison's disease) can present with varied symptoms.
  • Autoimmune causes are the most common etiology for primary adrenal insufficiency.

Observation:

  • An 11-year-old girl presented with symptoms suggestive of primary adrenal insufficiency.
  • Diagnostic workup revealed dilated cardiomyopathy.
  • Other causes of primary adrenal insufficiency were ruled out.

Findings:

  • Dilated cardiomyopathy is a rare complication of primary adrenal insufficiency.
  • Glucocorticoid replacement therapy led to significant recovery of cardiac function.
  • This is the first reported case in Syria.

Implications:

  • Early diagnosis and treatment of adrenal insufficiency are crucial.
  • Reversible cardiomyopathy can occur as a complication of primary adrenal insufficiency.
  • This case underscores the importance of cardiac monitoring in pediatric patients with Addison's disease.
Abstract

Keywords:
Dilated cardiomyopathyGlucocorticoidsPrimary adrenal cortex insufficiency

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