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Related Experiment Video

Updated: Feb 2, 2026

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model

Published on: October 27, 2020

Accidental hypothermia.

Peter Paal¹, Hermann Brugger², Giacomo Strapazzon²

¹Department of Anaesthesia and Intensive Care Medicine, Hospitallers Brothers Hospital, Salzburg, Austria.

Handbook of Clinical Neurology

|November 22, 2018

Summary

This summary is machine-generated.

Accidental hypothermia can make individuals appear lifeless but resuscitatable. Early, minimally invasive rewarming and extracorporeal life support (ECLS) significantly improve survival rates for hypothermic patients, even those in cardiac arrest.

Keywords:

accidental hypothermia avalanche cardiopulmonary bypass cardiopulmonary resuscitation cooling emergency medicine extracorporeal membrane oxygenation intensive care medicine rewarming trauma

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Area of Science:

Emergency Medicine
Critical Care Medicine
Physiology

Background:

Accidental hypothermia causes significant physiological changes, slowing vital functions as body temperature drops.
Deeply hypothermic individuals may present with absent vital signs but remain resuscitatable with appropriate medical intervention.

Purpose of the Study:

To highlight the potential of minimally invasive rewarming for non-arrested hypothermic patients.
To emphasize the critical role of extracorporeal life support (ECLS) in managing hypothermic cardiac arrest.
To advocate for structured protocols in prehospital and in-hospital management of hypothermia.

Main Methods:

Review of current management strategies for accidental hypothermia.
Discussion of minimally invasive rewarming techniques for stable hypothermic patients.
Analysis of the application and success of ECLS in hypothermic cardiac arrest cases.
Emphasis on continuous cardiopulmonary resuscitation (CPR) during transport for cardiac arrest patients.

Main Results:

Minimally invasive rewarming can decrease morbidity and mortality in non-arrested hypothermic patients.
ECLS has achieved near 100% survival rates in hypothermic cardiac arrest.
Structured protocols are essential for optimizing triage, transport, and treatment.

Conclusions:

Prompt and appropriate management, including advanced techniques like ECLS, is crucial for improving outcomes in accidental hypothermia.
Patients with hypothermia and risk factors for arrest, or those already in arrest, require specialized care and direct transfer to ECLS centers.
Standardized protocols for prehospital and in-hospital care are vital for effective hypothermia management.