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Updated: Feb 2, 2026

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
Published on: October 27, 2020
Consequences of perioperative hypothermia.
1Departments of General Anesthesiology and Outcomes Research, Anesthesiology Institute, Cleveland Clinic, Cleveland, OH, United States.
Perioperative hypothermia, a common complication affecting 20-70% of patients, increases risks like infections and prolonged recovery. Active skin warming is an efficient, cost-effective solution for maintaining normal body temperature during surgery.
Area of Science:
- Anesthesiology
- Critical Care Medicine
- Surgical Patient Care
Background:
- Perioperative hypothermia (body core temperature < 36.0°C) occurs in 20-70% of patients.
- Hypothermia is linked to increased surgical site infections, blood loss, coagulopathy, and prolonged recovery.
- Historically, perioperative warming was uncommon but is now recognized for its importance.
Purpose of the Study:
- To highlight the significance of preventing perioperative hypothermia.
- To emphasize the benefits of maintaining normothermia during the perioperative period.
- To review available warming methods and their efficacy.
Main Methods:
- Review of existing literature on perioperative hypothermia and warming strategies.
- Analysis of the incidence and consequences of hypothermia.
- Evaluation of different perioperative warming devices.
Main Results:
- Active skin warming identified as the most efficient method.
- Active skin warming is inexpensive, easy to use, and cost-effective.
- Maintaining normothermia is crucial for reducing perioperative morbidity.
Conclusions:
- Perioperative warming is essential to prevent complications.
- Active skin warming offers a favorable cost-benefit ratio.
- Monitoring central core temperature and implementing warming are vital for patient safety.
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