Related Experiment Video

Updated: Feb 2, 2026

Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence
10:06

Imaging Mycobacterium tuberculosis in Mice with Reporter Enzyme Fluorescence

Published on: February 26, 2018

7.8K

Primary cavitary tuberculosis in an infant

Zahide Yalaki1, Medine Ayşin Taşar1, Eren Yıldız1

  • 1Clinic of Pediatrics, Ankara Training and Research Hospital, Ankara, Turkey.

Turk Pediatri Arsivi
|November 22, 2018
PubMed

Insights

Pediatric tuberculosis can present unusually in infants, sometimes with rare cavitary lesions. Early diagnosis is key, even with atypical symptoms, to manage infant tuberculosis effectively.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Radiology

Background:

  • Tuberculosis (TB) in infants typically manifests as hilar lymphadenopathy and lung parenchymal changes.
  • Cavitary lesions are an uncommon presentation of TB in this age group.

Observation:

  • A six-month-old infant presented with fever and decreased breath sounds, initially diagnosed with lobar pneumonia.
  • Chest radiography showed right middle lobe pneumonic infiltration, but antibiotic treatment yielded no clinical improvement.
  • Computed tomography revealed extensive lymphadenopathy in the hilar, pretracheal, and subcarinal regions.

Findings:

  • Tuberculin and acid-fast bacilli tests were negative, but the quantiferon test was positive.
  • The infant's mother was diagnosed with active tuberculosis, indicating a likely source of infection.
  • The case highlights that primary cavitary tuberculosis can occur in infants, despite its rarity.

Implications:

  • Infant tuberculosis diagnosis requires considering atypical presentations beyond typical lymphadenopathy and lung changes.
  • Advanced imaging like CT scans is crucial for identifying subtle or unusual TB manifestations in infants.
  • Prompt diagnosis and treatment are vital, especially when family members have active tuberculosis, to prevent severe outcomes in infants.

Keywords:
Infantcavitationtuberculosis

More Related Videos

Separation and Fractionation of Culture Filtrate Proteins (CFPs) from Mycobacterium tuberculosis08:48

Separation and Fractionation of Culture Filtrate Proteins (CFPs) from Mycobacterium tuberculosis

Published on: July 11, 2025

591
Separation and Fractionation of Cell Wall and Cell Membrane Proteins from Mycobacterium tuberculosis for Downstream Protein Analysis06:14

Separation and Fractionation of Cell Wall and Cell Membrane Proteins from Mycobacterium tuberculosis for Downstream Protein Analysis

Published on: September 26, 2025

648

Related Concept Videos

Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
958
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.5K
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
622
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
295
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
1.1K
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
529