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[Pharmacotherapy of cough]
E Imhof1, E Russi, A P Perruchoud
1Abteilung für Pneumologie, Kantonsspital Basel.
Summary
Effective cough treatment requires identifying the cause. When the cause is unknown or cough disrupts sleep, centrally acting antitussives like dextromethorphan are recommended for symptomatic relief.
Area of Science:
- Pulmonology
- Pharmacology
Context:
- Cough is a common symptom with various underlying causes.
- Effective management hinges on accurate diagnosis and targeted therapy.
Purpose:
- To outline the optimal approach to cough treatment.
- To differentiate between etiological and symptomatic management strategies.
Summary:
- The primary treatment for cough involves identifying and addressing its specific cause, which typically leads to successful outcomes.
- When the etiology is unclear or the cough is debilitating, symptomatic treatment with centrally acting antitussives (e.g., dextromethorphan, opium alkaloids) is indicated.
- Evidence supporting the use of expectorants for cough treatment is scientifically lacking.
Impact:
- Provides a clear clinical guideline for managing cough effectively.
- Highlights the limitations of expectorants, guiding evidence-based prescribing practices.
- Emphasizes the importance of etiological diagnosis for optimal patient care.