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The Role of Medical Treatment in Chronic Subdural Hematoma

Amit Kumar Thotakura1, Nageswara Rao Marabathina1

  • 1Department of Neurosurgery, NRI Academy of Sciences, Guntur, Andhra Pradesh, India.

Asian Journal of Neurosurgery
|November 22, 2018
PubMed

Insights

Medical management for chronic subdural hematoma (CSDH) is reviewed, showing potential in selected patients. Further research, including randomized controlled trials, is needed to establish definitive treatment protocols for CSDH.

Area of Science:

  • Neurosurgery
  • Neurology
  • Pharmacology

Background:

  • Chronic subdural hematoma (CSDH) is a common neurosurgical condition.
  • Surgery is the established treatment, but medical management is being explored.
  • Limited acceptance and varying results exist for non-surgical CSDH treatment.

Purpose of the Study:

  • To provide a comprehensive overview of the medical management of CSDH.
  • To explore the role of pharmacological agents in CSDH pathophysiology.
  • To review primary medical treatment, adjuvant therapy, and recurrence management for CSDH.

Main Methods:

  • Literature review focusing on medical management of CSDH.
  • Analysis of drug actions within the CSDH pathophysiological cascade.
  • Categorization of reviewed literature into primary treatment, adjuvant therapy, and recurrence.

Main Results:

  • Medical treatment shows promise for a specific subset of CSDH patients.
  • Various drugs' actions in CSDH formation are detailed.
  • Factors influencing medical treatment outcomes and CSDH classifications are discussed.

Conclusions:

  • Medical management has a defined role in select chronic subdural hematoma cases.
  • High-quality, multicenter randomized controlled trials are essential.
  • Further research is required to establish standardized medical treatment protocols for CSDH.

Keywords:
Chronic subdural hematomaclassification of chronic subdural hematomaconservative managementmedical treatmentnonsurgical treatment

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