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Lung Involvement in Chronic Schistosomiasis with Bladder Squamous Cell Carcinoma
Emerging Infectious Diseases
|November 22, 2018
Summary
Schistosoma haematobium infection can cause lung issues, mimicking cancer spread. This case highlights chronic infection with squamous cell carcinoma in a Malian man.
Area of Science:
- Medical Parasitology
- Pulmonology
- Oncology
Background:
- Schistosoma haematobium is a parasitic worm endemic in parts of Africa, typically causing genitourinary disease.
- Pulmonary involvement is rare, and its association with malignancy is not well-established.
Observation:
- A 30-year-old man in Mali presented with symptoms suggestive of lung metastases.
- Imaging revealed pulmonary nodules, raising concern for malignancy.
Findings:
- Lung biopsies confirmed chronic Schistosoma haematobium infection.
- High-grade squamous cell carcinoma was also diagnosed.
- The pulmonary nodules were attributed to chronic parasitic inflammation, not metastases.
Implications:
- This case underscores the importance of considering parasitic infections in the differential diagnosis of pulmonary nodules, especially in endemic areas.
- Chronic Schistosoma haematobium infection may predispose to or coexist with lung cancer.
- Further research is needed to understand the link between schistosomiasis and lung carcinogenesis.
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