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Published on: August 29, 2017
Aging-associated perifollicular changes and calcium deposition in poodles
Vincenzo Miragliotta1, Sharon Buonamici1, Alessandra Coli1
1Department of Veterinary Sciences, University of Pisa, Viale delle Piagge 2, 56124, Pisa, Italy.
Background:
It is commonly accepted that canine dystrophic mineralization of the hair follicle glassy membrane can be seen in hyperadrenocorticism and as a senile change in poodles. Pathology textbooks define this change as deposition of calcium salts in the form of basophilic, amorphous, granular material along collagen fibrils.
Hypothesis/Objectives:
The aim was to evaluate whether the incidence of the lesion is specific to poodles and if it is always associated with calcium deposition.
Animals:
One hundred and forty-seven dogs divided into three groups: (i) 91 normal poodles; (ii) 40 dogs of other breeds; and (iii) 16 dogs with clinical/histopathological diagnosis of hyperadrenocorticism.
Methods And Materials:
Retrospective study; with haematoxylin and eosin, and von Kossa staining.
Results:
Our findings demonstrate that perifollicular changes of the hair follicle glassy membrane of poodles are not always associated with calcium deposition.
Conclusions And Clinical Importance:
A specific staining is needed to identify true calcium deposition when performing histological examination of the skin of poodles.
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