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Related Experiment Video

Updated: Feb 2, 2026

Methods for Acute and Subacute Murine Hindlimb Ischemia
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New concepts on acute ocular ischemia.

Rahul A Sharma1, Nancy J Newman2,3,4, Valérie Biousse2,3

  • 1Department of Ophthalmology, The University of Ottawa, Ottawa, Ontario, Canada.

Current Opinion in Neurology
|November 22, 2018
PubMed
Summary

Prompt recognition and stroke center referral are crucial for acute ocular ischemic events like transient monocular vision loss and retinal artery occlusions. Effective treatments remain limited, emphasizing immediate emergency management.

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Area of Science:

  • Ophthalmology
  • Neurology
  • Vascular Medicine

Background:

  • Acute ocular ischemic events present diagnostic and therapeutic challenges.
  • These events, including transient monocular vision loss and retinal artery occlusions, are often stroke equivalents requiring urgent evaluation.

Purpose of the Study:

  • To review recent advancements in managing acute ocular ischemic events.
  • To highlight the importance of immediate diagnosis and management strategies.

Main Methods:

  • Literature review of recent studies on ocular ischemic events.
  • Analysis of current diagnostic and therapeutic approaches.

Main Results:

  • Transient monocular vision loss and retinal artery occlusions necessitate immediate stroke workup.
  • Treatment options for central retinal artery occlusions are limited, with ongoing debate regarding thrombolytic use.
  • No definitive evidence supports therapies for nonarteritic anterior ischemic optic neuropathy, with a focus on ruling out giant cell arteritis.

Conclusions:

  • Effective treatments for retinal and optic nerve ischemia are still lacking.
  • Prompt recognition and referral to a stroke center are paramount for patients experiencing ocular ischemic emergencies.