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Adult-onset Buphthalmos in Down Syndrome
Sidney J Faria-E-Sousa1, Alexandre G Marques, Juliana Vieira
1Department of Ophthalmology, School of Medicine of Ribeirão Preto, University of São Paulo, Avenida Bandeirantes, Ribeirão Preto, São Paulo, Brazil.
Purpose:
To report a peculiar case of adult-onset buphthalmos.
Methods:
Review of the medical record of a 24-year-old patient with Down syndrome who developed buphthalmos in the left eye after corneal transplantation for keratoconus.
Results:
In the next 2 years after surgery, the operated eye evolved with chronic anterior uveitis that led to progressive peripheral synechiae, oscillating intraocular pressure, cataract, graft failure, and buphthalmos.
Conclusions:
The finding of buphthalmos of adult-onset in Down syndrome raises important issues concerning the classification of this eye condition and the responsibility for detecting and monitoring eyes with glaucoma in individuals with chromosome 21 trisomy.
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