Related Experiment Video
Updated: Feb 2, 2026

07:11
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
6.9K
Vection Responses in Patients With Early Glaucoma
Taylor A Brin1,2, Luminita Tarita-Nistor1, Esther G González1,2
1Krembil Research Institute, Toronto Western Hospital.
Journal of Glaucoma
|November 22, 2018
Summary
Patients with glaucoma show longer vection latencies, indicating altered visual-motor responses. However, the combined index of structure and function (CSFI) did not correlate with these vection measures in our study.
Area of Science:
- Ophthalmology
- Neuroscience
- Human Perception
Background:
- Glaucoma is a progressive optic neuropathy characterized by retinal ganglion cell loss.
- Previous research indicates that patients with early glaucoma exhibit prolonged vection latencies.
Purpose of the Study:
- To investigate the relationship between the combined index of structure and function (CSFI) and vection responses in glaucoma patients.
- To determine if CSFI can explain the longer vection latencies observed in early glaucoma.
Main Methods:
- Two experiments were conducted using a back-projected screen and Oculus Rift system to elicit roll and circular vection.
- Vection latency, duration, and strength were measured, alongside subjective tilt and vection ratings.
- Measurements were compared with the CSFI, derived from visual field and optical coherence tomography data.
Main Results:
- Vection latency was significantly longer in glaucoma patients compared to controls in both experiments (P=0.02).
- The CSFI showed no significant correlation with vection latency, duration, or strength (P=0.06).
Conclusions:
- The study replicated findings of prolonged vection responses in glaucoma patients.
- The CSFI is not a reliable predictor of altered vection responses in glaucoma.
Related Concept Videos
Glaucoma: Overview
1.4K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.4K
Open Angle Glaucoma: Treatment
996
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
996
Angle Closure Glaucoma: Treatment
1.3K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.3K
Responses to Gravity and Touch
41.9K
Gravitropism: Plant Responses to Gravity
41.9K
Humoral Immune Responses
83.9K
Overview
83.9K
Responses to Drought and Flooding
12.1K
Water plays a significant role in the life cycle of plants. However, insufficient or excess of water can be detrimental and pose a serious threat to plants.
12.1K

