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Potassium Iodide for Cutaneous Inflammatory Disorders: A Monocentric, Retrospective Study.

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Potassium iodide (KI) showed a modest therapeutic response in about one-third of dermatology patients. While side effects were mild, efficacy of KI for various granulomatous skin conditions needs further investigation.

Keywords:
Erythema nodosumGranuloma anulareInflammatory dermatosisNecrobiosis lipoidicaNodular vasculitisPotassium iodide

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Area of Science:

  • Dermatology
  • Pharmacology

Background:

  • Potassium iodide (KI) is a long-standing dermatological treatment.
  • Recent data on KI efficacy is limited.

Purpose of the Study:

  • To retrospectively evaluate the therapeutic response to Potassium iodide (KI).

Main Methods:

  • Retrospective analysis of 35 patients treated with KI over 20 years (1998-2017).
  • KI was prescribed for conditions including erythema nodosum and sarcoidosis.

Main Results:

  • Improvement observed in approximately one-third of patients.
  • No response in 14 patients; disease progression in 9.
  • Adverse events documented in 16 out of 35 patients.

Conclusions:

  • KI demonstrated limited efficacy, with improvement in only about a third of cases.
  • Mild side effects were noted in nearly half of the patients.