Nebulization versus standard application for topical anaesthesia during flexible bronchoscopy under moderate sedation...

Area of Science:

• Pulmonology
• Anesthesiology
• Medical Devices

Background:

• Endobronchial lidocaine is standard for cough suppression during bronchoscopy.
• Nebulized lidocaine offers advantages in deep sedation but lacks data for moderate sedation.
• This study investigates nebulized lidocaine's safety and tolerability in moderate sedation bronchoscopies.

Purpose of the Study:

• To compare the tolerability and safety of nebulized lidocaine versus conventional syringe administration.
• To evaluate lidocaine and sedative drug consumption in both methods.
• To assess patient outcomes including oxygenation and complication rates.

Main Methods:

• Randomized controlled trial comparing nebulized versus syringe lidocaine administration.
• Sixty patients undergoing diagnostic bronchoscopy were enrolled.
• Endpoints included drug consumption, patient tolerance, safety, oxygen saturation, and complication rates.

Main Results:

• Nebulized lidocaine required significantly lower doses (164.7 mg) compared to syringe (250.4 mg).
• No difference in sedative drug dosage was observed between groups.
• Nebulizer group showed better oxygen saturation (96.19%) and fewer complications (0.3) versus syringe group (94.21%, 1.17).

Conclusions:

• Nebulized endobronchial lidocaine is well-tolerated in moderate sedation bronchoscopies.
• This method reduces lidocaine consumption and complication rates.
• Nebulized lidocaine improves patient oxygenation compared to syringe administration.