The spectrum of the dyslipidemia in Colombia: The PURE study

Paul A Camacho1, Johanna Otero2, Maritza Pérez3

  • 1Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, Colombia; Universidad Autónoma de Bucaramanga (UNAB), Bucaramanga, Colombia.

Insights

Dyslipidemia, a major cardiovascular disease risk factor, affects 87.7% of Colombian adults. This lipid profile abnormality is more prevalent in rural, poorer regions and among those with lower socioeconomic status.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Dyslipidemia is a significant risk factor for cardiovascular diseases (CVD), contributing to a third of ischemic heart disease globally.
  • In Colombia, dyslipidemia is the leading cause of cardiovascular deaths, yet no large-scale prevalence studies existed.
  • The study addresses the need to understand dyslipidemia's magnitude in Colombia, a nation with diverse regional, geographic, and socioeconomic disparities.

Purpose of the Study:

  • To determine the prevalence of dyslipidemia in a representative Colombian population.
  • To identify demographic and socioeconomic factors associated with dyslipidemia in Colombia.
  • To inform public health strategies for CVD prevention in Colombia.

Main Methods:

  • A cross-sectional study was conducted on 6628 individuals aged 35 to 70 years across four Colombian regions.
  • Data on lipid profiles and socioeconomic factors were collected.
  • Prevalence rates and associated factors were analyzed.

Main Results:

  • The overall prevalence of dyslipidemia was 87.7% in the Colombian population studied.
  • Higher prevalence was observed in individuals over 50, males, rural residents, and those with lower education and income.
  • High non-HDL cholesterol was the most common abnormality (75.3%), with lipid levels varying across regions based on health needs index.

Conclusions:

  • Colombia exhibits a high prevalence of abnormal lipid profiles, indicating a significant public health concern.
  • Dyslipidemia is more common in rural, poorer regions and among individuals of lower socioeconomic status.
  • Targeted strategies are crucial to address adverse lipid profiles and reduce CVD, especially in vulnerable Colombian populations.
Abstract

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