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The spectrum of the dyslipidemia in Colombia: The PURE study
Paul A Camacho1, Johanna Otero2, Maritza Pérez3
1Fundación Oftalmológica de Santander (FOSCAL), Floridablanca, Colombia; Universidad Autónoma de Bucaramanga (UNAB), Bucaramanga, Colombia.
Insights
Dyslipidemia, a major cardiovascular disease risk factor, affects 87.7% of Colombian adults. This lipid profile abnormality is more prevalent in rural, poorer regions and among those with lower socioeconomic status.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Dyslipidemia is a significant risk factor for cardiovascular diseases (CVD), contributing to a third of ischemic heart disease globally.
- In Colombia, dyslipidemia is the leading cause of cardiovascular deaths, yet no large-scale prevalence studies existed.
- The study addresses the need to understand dyslipidemia's magnitude in Colombia, a nation with diverse regional, geographic, and socioeconomic disparities.
Purpose of the Study:
- To determine the prevalence of dyslipidemia in a representative Colombian population.
- To identify demographic and socioeconomic factors associated with dyslipidemia in Colombia.
- To inform public health strategies for CVD prevention in Colombia.
Main Methods:
- A cross-sectional study was conducted on 6628 individuals aged 35 to 70 years across four Colombian regions.
- Data on lipid profiles and socioeconomic factors were collected.
- Prevalence rates and associated factors were analyzed.
Main Results:
- The overall prevalence of dyslipidemia was 87.7% in the Colombian population studied.
- Higher prevalence was observed in individuals over 50, males, rural residents, and those with lower education and income.
- High non-HDL cholesterol was the most common abnormality (75.3%), with lipid levels varying across regions based on health needs index.
Conclusions:
- Colombia exhibits a high prevalence of abnormal lipid profiles, indicating a significant public health concern.
- Dyslipidemia is more common in rural, poorer regions and among individuals of lower socioeconomic status.
- Targeted strategies are crucial to address adverse lipid profiles and reduce CVD, especially in vulnerable Colombian populations.
Background:
Dyslipidemia is a major risk factor for cardiovascular diseases (CVD). Worldwide, a third of ischemic heart disease is due to abnormal cholesterol levels and it is the most common cause of cardiovascular deaths in Colombia. In Colombia, no representative, large-scale study has assessed the prevalence of dyslipidemia. The aim of the present analysis was to identify the magnitude of the problem in Colombia, a middle-income-country with large regional, geographic, and socio-economical differences.
Material And Methods:
The sample comprised 6628 individuals aged 35 to 70 years (mean age 50.7 years, 64.1% women) residing in the four Colombian regions.
Results:
The overall prevalence of dyslipidemia was 87.7% and was substantially higher among participants older than 50 years, male, rural residents, and those with a lower level of education (66.8%), and with a lower income (66.4%). High non HDL-c was the most common abnormality (75.3%). The values of total cholesterol and non-HDL-cholesterol were higher in areas with the lowest health needs index than in the areas with intermediate and highest health need index, the isolated HDL-c value was much lower.
Conclusion:
Colombia has a high prevalence of abnormalities of the lipid profile. The causes of the high rates of dyslipidemia were not well define in this study, but were more common in rural and poorer regions and among those with lower socio-economical status. Strategies to tackle the adverse lipid profile to reduce CVD are needed in Colombia, particularly in rural areas and among the areas with the higher health need index.
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