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Treatment of caesarean section scar pregnancy with systemic administration of methotrexate
Huili Yang1, Fuli Li1, Ping Zhang2
1Obstetrics and Gynecology Department, Jinan Central Hospital Affiliated to Shandong University, Jinan, China.
Abstract:
To observe and analyze the therapeutic effect of systemic administration of methotrexate on caesarean section scar pregnancy. The 160 patients who had been confirmed with caesarean section scar pregnancy in our hospital were selected research objects. They were randomly divided into two groups (research group and control group), each containing 80 patients. The research group was subjected to systemic administration of methotrexate, while control group was applied with local administration of methotrexate. The total treatment effective rates of two groups were observed and compared. The total treatment effective rate of research group was higher than that of control group, p<0.05; in terms of time required for a-HCG restoring to normal state, the research group was significantly shorter than control group, p<0.05; the time required for disappearing of scar lump for research group was shorter than that of control group, p<0.05. No complications were observed for both groups. Systemic administration of methotrexate can significantly improve the curative effect for patients with caesarean section scar pregnancy.
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