Related Experiment Video
Updated: Feb 2, 2026

Design and Development of a Model to Study the Effect of Supplemental Oxygen on the Cystic Fibrosis Airway Microbiome
Published on: August 3, 2021
Developing Digital Games to Address Airway Clearance Therapy in Children With Cystic Fibrosis: Participatory Design
Fabio Balli1,2
1Breathing Games, Montreal, QC, Canada.
Background:
Children affected with cystic fibrosis do respiratory exercises to release the mucus stuck in their lungs.
Objective:
The objective of our study was to develop prototypes of digital games that use breath pressure to make this daily physiotherapy more fun.
Methods:
We used a participatory design approach and organized short events to invite contributors from different disciplines to develop game prototypes. From the 6 prototypes, 3 were tested by 10 children during a prestudy. The source code of the games, of which 2 continue to be developed, has been released on the internet under fair use licenses.
Results:
We discuss 7 themes of importance in designing games for health, combining our experience with a review a posteriori of literature.
Conclusions:
This study provides examples of games and their pitfalls as well as recommendations to create games for health in a participatory approach that enables everyone to improve and adapt the work done.
Related Concept Videos
Cystic Fibrosis: Pathogenesis
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
Cystic Fibrosis: Management
Sinus disease and chronic...
Strategies for Assessing and Addressing Confounding
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
Hepatic Drug Clearance: Restrictive and Nonrestrictive Clearance
Most drugs undergo restrictive clearance, which is proportional to the...
Renal Clearance
Renal clearance refers to the volume of plasma cleared of a specific substance, such as creatinine, per unit of time. To measure clearance, urine samples are collected over a 24-hour period during each bladder voiding, followed by a single blood sample at the...
Group Design

