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Related Concept Videos

Communication01:03

Communication

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Communication between two animals occurs when one animal transmits an information signal that causes a change in the animal that receives the information. Organisms communicate with one another in a host of different ways. Signals can be auditory, chemical, visual, tactile, or a combination of these. Communication is a critical behavioral adaptation that promotes survival, growth, and reproduction.
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Communication01:28

Communication

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Sharing information, concepts, and emotions to foster mutual understanding is communication. The sender, recipient, and transaction must be considered in this manner. The sender is the person who shares the message, the recipient is the person who receives and understands the message, and the transaction is the method used to deliver the message and the variables that affect the communication's context and surroundings. The nurse-client connection is built on therapeutic communication.
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Neuronal Communication01:28

Neuronal Communication

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Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
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Therapeutic Communication01:30

Therapeutic Communication

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Communication is a lifelong learning process. Through therapeutic communication, nurses can collect relevant assessment data, provide education and counseling, and interact during nursing interventions. Sending and receiving messages occur through verbal and nonverbal communication techniques and can happen separately or simultaneously.
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Barriers to Effective Communication II01:21

Barriers to Effective Communication II

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The barriers to effective communication also include cultural barriers, semantic barriers, gender barriers, and time constraints.
Cultural barriers:
Differences in values, beliefs, religion, knowledge, and tradition can significantly impact communication. Awareness of nonverbal cues is critical, especially when conversing with a patient from a different culture. What appears appropriate in one culture may be inappropriate in another.
Semantic barriers:
As a result of their tendency to use...
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Channels of Non-Verbal Communication01:28

Channels of Non-Verbal Communication

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Non-verbal communication plays a critical role in human interaction, influencing how individuals perceive emotions and psychological states. It operates through four primary channels: facial expressions, eye contact, body language, and touch. These non-verbal cues help convey meaning beyond spoken language and are often culturally influenced.Facial Expressions and Emotional RecognitionFacial expressions are among the most powerful and universal forms of non-verbal communication. Research has...
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Related Experiment Video

Updated: Feb 2, 2026

The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia
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The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia

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Inter-tissue communication in cancer cachexia.

Josep M Argilés1,2, Britta Stemmler3, Francisco J López-Soriano1,2

  • 1Cancer Research Group, Departament de Bioquímica i Biomedicina Molecular, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.

Nature Reviews. Endocrinology
|November 23, 2018
PubMed
Summary

Cancer cachexia involves multi-organ wasting, including muscle and adipose tissue loss, driven by inter-tissue communication. Understanding these signals is key to developing new cancer cachexia therapies.

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Area of Science:

  • Oncology
  • Metabolism
  • Physiology

Background:

  • Cachexia is a complex systemic condition common in cancer patients.
  • It involves significant loss of body weight, muscle mass, and adipose tissue.
  • Systemic inflammation, anorexia, and increased energy expenditure are characteristic features.

Purpose of the Study:

  • To review the role of non-muscle tissues in cancer cachexia.
  • To examine inter-tissue communication in the context of cancer cachexia.
  • To discuss emerging therapeutic strategies targeting cancer cachexia.

Main Methods:

  • Literature review of existing studies on cancer cachexia.
  • Analysis of research on inter-organ communication in neoplastic diseases.
  • Synthesis of findings on soluble factors secreted by various tissues.

Main Results:

  • Cancer cachexia affects multiple organs beyond skeletal muscle, including adipose tissue, bone, brain, liver, gut, and heart.
  • Tumor and non-muscle tissues secrete factors that induce skeletal muscle wasting.
  • Muscle tissue also releases factors influencing other tissues' metabolism during cancer.

Conclusions:

  • Non-muscle tissues and their communication play a critical role in cancer cachexia.
  • Targeting inter-tissue signaling presents a promising avenue for novel therapeutic interventions.
  • Further research into these complex interactions is essential for effective treatment development.