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Peritoneal Tuberculosis in Infants: Diagnostic Challenges
Ndeye Aby Ndoye1,2, Papa Alassane Mbaye1,2, Jacques Noel Tendeng3,4
1Department of Pediatric Surgery of Medecine, Universite Cheikh Anta Diop, Dakar, Senegal.
Insights
Abdominal tuberculosis is rare in infants. This study highlights two infant cases of peritoneal tuberculosis, emphasizing diagnosis and successful treatment with anti-tuberculosis therapy.
Area of Science:
- Pediatrics
- Infectious Diseases
- Gastroenterology
Background:
- Abdominal tuberculosis is uncommon in immunocompetent infants, presenting diagnostic challenges.
- Peritoneal tuberculosis can mimic other pediatric surgical emergencies like intussusception.
Observation:
- Two infants (6 and 8 months) presented with symptoms suggestive of intussusception, leading to exploratory laparotomy.
- Intraoperative findings in the first infant revealed characteristic peritoneal tuberculosis lesions with granulations.
Findings:
- Histopathological examination confirmed peritoneal tuberculosis in both infants.
- The first infant had a positive Tuberculin intradermal reaction (IDRt) and positive tuberculous culture.
- The second infant had negative IDRt and GeneXpert tests, underscoring the need for histopathology.
Implications:
- This case series emphasizes the importance of considering abdominal tuberculosis in infants with unclear abdominal pathologies.
- Prompt diagnosis and initiation of tuberculostatic therapy led to favorable outcomes in both cases.
- Highlights the diagnostic utility of histopathology even with negative microbiological or rapid tests.
Abstract:
Abdominal tuberculosis is rare in immunocompetent infants. We report on two infants with peritoneal tuberculosis (6 and 8 months) who underwent laparotomy for suspected intussusception. In the first patient, characteristic lesions of peritoneal tuberculosis were observed intraoperatively with presence of multiple granulations. Tuberculin intradermal reaction (IDRt) was positive and tuberculous contagium could be cultured. In the second patient, the IDRt and GeneXpert tests were negative. In both patients, the histopathological examination of the biopsy specimens confirmed the diagnosis of peritoneal tuberculosis. The clinical courses under tuberculostatic therapy were favorable in both cases.
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