The Role of Surgical Debridement in Cases of Refractory Malignant Otitis Externa
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Published on: March 2, 2020
Jaskaran Singh1, Bhanu Bhardwaj2
1Sri Guru Ram Das Institute of Health Sciences and Research Amritsar, HIG 202, Sector 71, Mohali, 160071 India.
Abstract:
Malignant Otitis externa is a necrotizing condition of external ear involving causing the osteomyelitis of the bone and surrounding soft tissue leading to multiple cranial nerve palsies. Though most patients respond to oral ciprofloxacin but due to emerging resistance cases of refractory malignant otitis externa which are unresponsive to antibiotic therapy for at least 6 weeks are being encountered lately. A study of 20 patients of refractory malignant otitis Externa was conducted at a tertiary care centre in north India; 10 patients were randomly allotted in group A and group B each. Group A was subjected to i/v ceftazidine 1 gm bd with oral ciprofloxacin 750 mg bd and Group B was subjected to surgical debridement with oral ciprofloxacin 750 mg bd. The improvement in symptoms was tabulated and statistical analysis was done using Mann-Whitney U test. There was better resolution of nocturnal pain in patients of group B who underwent surgical debridement although existing facial palsy didn't improve in both the groups. The improvement of symptoms in group B was statistically significant with P ≤ 0.05. We strongly recommend the role of surgical debridement in cases of refractory malignant otitis externa to relieve the patient of nocturnal pain. As the sample size of the study is small we are looking forward to the compilation of a multi institutional data so that a consensus on definitive protocol in cases unresponsive to oral multidrug therapy can be established.
Insights
Refractory malignant otitis externa, a severe ear infection, often requires more than antibiotics. Surgical debridement significantly improved nocturnal pain in a study, suggesting its value in resistant cases.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Surgical Oncology
Background:
- Malignant otitis externa (MOE) is a serious necrotizing infection of the external ear canal.
- Osteomyelitis and cranial nerve palsies are common complications of MOE.
- Emerging antibiotic resistance leads to refractory MOE cases unresponsive to standard therapy.
Purpose of the Study:
- To evaluate the efficacy of surgical debridement compared to intravenous antibiotics in treating refractory malignant otitis externa.
- To assess symptom resolution, particularly nocturnal pain and facial palsy, in patients with refractory MOE.
Main Methods:
- A randomized study of 20 patients with refractory MOE was conducted.
- Group A received intravenous ceftazidime and oral ciprofloxacin.
- Group B underwent surgical debridement with oral ciprofloxacin.
Main Results:
- Surgical debridement (Group B) showed statistically significant improvement in nocturnal pain (P ≤ 0.05).
- Facial palsy did not improve in either treatment group.
- Overall symptom improvement was more pronounced in the surgical debridement group.
Conclusions:
- Surgical debridement is a recommended intervention for refractory malignant otitis externa to alleviate nocturnal pain.
- Further multi-institutional studies are needed to establish a definitive treatment protocol for antibiotic-unresponsive MOE.
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