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Updated: Feb 2, 2026

Activation of Apoptosis by Cytoplasmic Microinjection of Cytochrome c
Published on: June 29, 2011
Genome Analysis of Cytochrome in Dinotefuran-Treated Apolygus lucorum (Meyer-Dür)
Shaoying Wu1,2, Denghui Deng3, Wayne Jiang4
1College of Plant Protection, Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests (Hainan University), Ministry of Education, Haikou, 570228, China. wsywsy6000@126.com.
Abstract:
In this study, two CYP genes, CYP395G1 and CYP4EY1, were analyzed in Apolygus lucorum (Hemiptera: Miridae). The expression pattern in different developmental stages of both CYP395G1 and CYP4EY1 revealed that first instar nymphs possessed the highest gene-transcript levels. After 12 h of dinotefuran treatments, the expression levels of CYP395G1 increased by 1.92-fold, while the CYP4EY1 expression decreased. It was observed that the sensitivities of dinotefuran to laboratory strains from F0 to F9 and the mRNA expression levels of CYP395G1 in the F9 dinotefuran selected strain were higher when compared to the control strain. The results suggest that CYP395G1 was possibly a candidate P450 that was involved in dinotefuran detoxification. The dinotefuran resistant strain of A. lucorum was difficult to increase, due to its special molecular structure of dinotefuran compared with other neonicotinoids.
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