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Published on: June 18, 2020
Non-Hepatic Abdominal Surgery in Patients with Cirrhotic Liver Disease
Laura Hickman1, Lauren Tanner2, John Christein1
1Department of Surgery, Division of Gastrointestinal Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Insights
Cirrhotic liver disease increases surgical risks. Patients with mild liver dysfunction (MELD <12 or Child A) can safely undergo elective surgery with proper education, while severe cases (MELD >20 or Child C) require transplantation first.
Area of Science:
- Hepatology
- Surgical Gastroenterology
- Critical Care Medicine
Background:
- Cirrhotic liver disease significantly impacts peri-operative outcomes in general surgery.
- Liver dysfunction requires careful assessment and management before elective surgical procedures.
Purpose of the Study:
- To evaluate the peri-operative risks associated with cirrhotic liver disease.
- To provide guidance on surgical management strategies for patients with varying degrees of liver dysfunction.
Main Methods:
- Review of peri-operative morbidity and mortality in general surgical patients with cirrhotic liver disease.
- Stratification of surgical risk based on MELD scores and Child-Pugh classification.
Main Results:
- Patients with MELD <12 or Child A cirrhosis have increased risks but are generally safe for elective surgery with patient education.
- Patients with MELD >20 or Child C cirrhosis face over 40% mortality, necessitating transplantation before elective procedures.
- Laparoscopic surgery is a feasible and safe option for cirrhotic patients.
Conclusions:
- Early recognition and optimization of liver dysfunction are crucial for surgical patients.
- Risk stratification using MELD and Child-Pugh classifications guides peri-operative decision-making in cirrhosis.
- Appropriate management, including transplantation and surgical approach selection, can improve outcomes for cirrhotic patients undergoing surgery.
Abstract:
Cirrhotic liver disease is an important cause of peri-operative morbidity and mortality in general surgical patients. Early recognition and optimization of liver dysfunction is imperative before any elective surgery. Patients with MELD <12 or classified as Child A have a higher morbidity and mortality than matched controls without liver dysfunction, but are generally safe for elective procedures with appropriate patient education. Patients with MELD >20 or classified as Child C should undergo transplantation before any elective procedure given mortality exceeds 40%. Laparoscopic procedures are feasible and safe in cirrhotic patients.
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