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Updated: Feb 2, 2026

Analysis of Developing Tooth Germ Innervation Using Microfluidic Co-culture Devices
Published on: August 14, 2015
[The role of bone morphogenetic protein signaling pathway in tooth root development]
Cang-Wei Liu1, Yi-Jun Zhou1, Guang-Xing Yan1
1Dept. of Oral Pathology, School and Hospital of Stomatology, Jilin University, Key Laboratory of Tooth Development and Bone Remodeling of Jilin Province, Changchun 130021, China.
Abstract:
The bone morphogenetic protein (BMP) family is an important factor in the regulation of cell ular life activities and in the development of almost all tissues. BMP-mediated signaling plays an important role in tooth root development, which is a part of tooth development. Epithelial and mesenchymal interactions are involved in tooth root development, but the BMP signaling pathway has a different effect on tooth root development in epithelial and mesenchymal. This review summarizes the advances of BMP signaling in tooth root development.
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