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Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
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An Unsupervised Smart App-Optimized HIV Self-Testing Program in Montreal, Canada: Cross-Sectional Study.

Nitika Pant Pai1,2, Megan Smallwood2, Laurence Desjardins3

  • 1Department of Medicine, McGill University, Montreal, QC, Canada.

Journal of Medical Internet Research
|November 23, 2018
PubMed
Summary
This summary is machine-generated.

The HIVSmart! app and oral HIV self-testing strategy proved feasible and acceptable for men who have sex with men in Montreal. This innovative approach effectively links individuals to care, improving public health outcomes.

Keywords:
HIVMSMfeasibilityimpactmobile phoneself-testing

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Area of Science:

  • Public Health
  • Digital Health
  • Infectious Disease Management

Background:

  • World Health Organization recommends HIV self-testing, but Canada lacks approval for these tests.
  • Existing HIV self-tests have insufficient support for counseling, interpretation, and care linkage.
  • The HIVSmart! app was developed to address these gaps in HIV self-testing support.

Purpose of the Study:

  • To evaluate the feasibility and acceptability of an app-optimized oral HIV self-testing strategy.
  • To assess the strategy's effectiveness in linking men who have sex with men (MSM) to care.
  • To test the strategy in a real-world setting at a sexual health clinic in Montreal.

Main Methods:

  • A strategy combining an investigational oral HIV self-test with the HIVSmart! app was offered to participants.
  • Participants underwent self-testing in a simulated unsupervised home environment.
  • Feasibility was measured by completion rates (test conduct, interpretation, linkage to care), acceptability, and preference.

Main Results:

  • High feasibility (96.6% completion rate) and acceptability (98.5%) were observed in 451 MSM participants.
  • The HIVSmart! app was found useful by 98.8% of participants.
  • Rapid linkage to care was achieved for all participants who tested positive (0.7%).

Conclusions:

  • The HIVSmart! app-optimized HIV self-testing strategy is feasible, acceptable, and preferred by MSM in Montreal.
  • The app facilitates self-testing, interpretation, result storage, and rapid linkage to care.
  • This strategy has the potential for adaptation to diverse at-risk populations globally, enhancing public health impact.