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Never seen before? Opisthorchiasis and Clonorchiasis
Christoph F Dietrich1,2, Nathan S S Atkinson3, W J Lee4
1Department of Internal Medicine 2, Caritas-Krankenhaus, Bad Mergentheim, Germany.
Summary
European clinicians need to recognize parasitic liver fluke infections like Clonorchis sinensis and Opisthorchis species due to increased migration. This review details their clinical and imaging features and treatment options.
Area of Science:
- Medical parasitology
- Infectious diseases
- Radiology
Background:
- Parasitic diseases are uncommon in Europe, leading to unfamiliarity among clinicians regarding their presentation.
- Increased global migration necessitates improved recognition of parasitic infections by healthcare professionals.
- Previous work covered cystic echinococcosis, schistosomiasis, fascioliasis, and ascariasis.
Purpose of the Study:
- To describe the clinical and imaging features of small liver fluke infections.
- To outline current therapeutic strategies for these infections.
- To enhance diagnostic capabilities for Clonorchis sinensis, Opisthorchis viverrini, Opisthorchis felineus, and other Opisthorchis species.
Main Methods:
- Review of clinical case data.
- Analysis of radiological imaging findings.
- Compilation of current treatment guidelines and literature.
Main Results:
- Detailed descriptions of the characteristic clinical presentations of Clonorchis sinensis and Opisthorchis species infections.
- Illustrations and explanations of key imaging findings (e.g., ultrasonography, CT, MRI).
- Summary of effective antiparasitic drug choices and management protocols.
Conclusions:
- Early and accurate diagnosis of liver fluke infections is crucial for effective patient management.
- Familiarity with the specific clinical and imaging hallmarks aids in timely identification.
- This information empowers European clinicians to better manage these neglected tropical diseases.

