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Related Concept Videos

Schemas01:42

Schemas

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A schema is a mental construct consisting of a cluster or collection of related concepts (Bartlett, 1932). There are many different types of schemata, and they all have one thing in common: schemata are a method of organizing information that allows the brain to work more efficiently. When a schema is activated, the brain makes immediate assumptions about the person or object being observed.
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A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
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A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

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Updates in Melanoma.

Elisabeth Hamelin Tracey1, Alok Vij1

  • 1Department of Dermatology, Dermatology and Plastic Surgery Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk A61, Cleveland, OH 44195, USA.

Dermatologic Clinics
|November 24, 2018
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Summary
This summary is machine-generated.

Skin cancer, particularly melanoma, is a growing epidemic. Advances in understanding its causes are improving risk assessment and leading to new treatments for advanced cases.

Keywords:
Gene expression profilingImmunotherapyMelanomaMelanoma stagingSkin cancerTargeted therapy for melanoma

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Area of Science:

  • Oncology
  • Dermatology
  • Cancer Research

Background:

  • Skin cancer, especially melanoma, is a significant public health concern in the US.
  • Understanding the underlying mechanisms of melanoma is crucial for effective management.
  • Current diagnostic and therapeutic strategies require enhancement to address the rising incidence.

Purpose of the Study:

  • To highlight recent advancements in melanoma pathophysiology.
  • To discuss improvements in risk stratification for melanoma patients.
  • To introduce novel diagnostic and therapeutic approaches for advanced melanoma.

Main Methods:

  • Review of recent scientific literature on melanoma.
  • Analysis of updated American Joint Committee on Cancer (AJCC) criteria.
  • Evaluation of emerging diagnostic technologies and treatment modalities.

Main Results:

  • Revised AJCC criteria offer improved melanoma risk stratification.
  • New diagnostic tests identify high-risk patients beyond initial staging.
  • Novel treatments show promise for patients with advanced melanoma.

Conclusions:

  • Advances in melanoma understanding are transforming patient care.
  • Improved risk assessment and targeted therapies offer new hope.
  • Continued research is vital to combat the skin cancer epidemic.