Related Experiment Video
Updated: Feb 2, 2026

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
Published on: November 30, 2022
Synthesis and characterization of Ni(II) complex functionalized silica-based magnetic nanocatalyst and its
Mohaddeseh Shahabi Nejad1, Neda Seyedi2, Hassan Sheibani3
1Department of Chemistry, Shahid Bahonar University of Kerman, Kerman, 76169, Iran.
Abstract:
A new magnetically recoverable silica-based nickel(II) nanocatalyst was synthesized by a simple cost-effective procedure, which was characterized by TEM, SEM, XRD, VSM analysis, and FT-IR spectrophotometry. The catalytic activity of the prepared Ni(II) nanocatalyst was tested in two complementary reactions: C-N Chan-Lam cross-coupling of phenylboronic acid with aryl amines and C-C Suzuki-Miyaura cross-coupling reaction of phenylboronic acid with aryl halides. The catalyst was easily recovered by magnetic separation and reused for five times. It demonstrated better catalytic activity in the C-N Chan-Lam reaction compared to C-C Suzuki-Miyaura reaction. Ease of recovery and reusability up to five cycles without noticeable loss of performance in the C-N cross-coupling reaction make the present protocol beneficial both industrially and environmentally. In this paper, a new magnetically recoverable silica-based nickel(II) nanocatalyst was synthesized and applied in two complementary reactions: C-C Suzuki-Miyaura reaction and C-N Chan-Lam reaction. The difference in catalytic activity makes it possible to use this catalyst for cases that are prone to both reactions and selectively create the desired product.
More Related Videos
07:20Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
11:44Mizoroki-Heck Cross-coupling Reactions Catalyzed by Dichloro{bis[1,1',1''-phosphinetriyltripiperidine]}palladium Under Mild Reaction Conditions
Published on: March 20, 2014
Related Concept Videos
Synthesis and Decomposition Reactions
Crossed Aldol Reaction Using Weak Bases
Crossed Aldol Reaction Using Strong Bases: Directed Aldol Reaction
Coupled Reactions
Energy in adenosine triphosphate or ATP molecules is easily accessible to do work. ATP powers the majority of energy-requiring cellular reactions....
Crossed Aldol Reactions: Overview
Acids, Bases and Neutralization Reactions