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Updated: Feb 2, 2026

Preparation of Decellularized Kidney Scaffolds in Rats
Published on: March 18, 2021
Relationship between Early Postmortem Interval and Electrical Conductivity of Rat Liver, Spleen and Kidney after
1School of Forensic Medicine, Henan University of Science and Technology, Luoyang 471003, Henan Province, China.
Objectives:
To determine the electrical conductivity (EC) of the liver, spleen and kidney of rats at different postmortem intervals (PMIs) within 24 hours for investigating the relationship between EC of different organs and early PMI.
Methods:
Totally 45 SD rats were sacrificed by cervical dislocation and kept at a constant temperature of 25 ℃. Tissues were taken from the liver, spleen, and kidney of rats at 0, 3, 6, 9, 12, 15, 18, 21 and 24 h. Impregnating solution with a mass concentration 0.1 g/mL was prepared using deionized water. The EC value of impregnating solution with different organs was separately determined. The regression equations of EC and PMI for different organs were established, respectively. The relationship between EC of different organs and early PMI was analysed in deceased rats.
Results:
The relationship between PMI and EC of the liver and spleen was well fitted with the linear equation. The liver showed the best fitting degree followed by the spleen, while the EC of the kidney showed no significant changes within 24 h. There was a good linear relationship between early PMI and the EC of the liver and spleen.
Conclusions:
A good linear relationship between early PMI and the EC of the liver and spleen can be found in rats after death, which can be used for the early PMI estimation.
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