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Updated: Feb 2, 2026

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TGF-beta/TGF-beta RII/CLC-3 axis promotes cognitive disorders in diabetes

Feiyan Fan1, Jing Qi1, Nan Liu1

  • 1Department of Experimental Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi\'an, 710038, Shanxi, China.

Frontiers in Bioscience (Landmark Edition)
|November 24, 2018
PubMed
Summary

Transforming growth factor beta (TGF-beta) and Chloride channel-3 (CLC-3) are linked to cognitive decline in diabetic encephalopathy. TGF-beta signaling may regulate CLC-3 expression, impacting neuronal survival.

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