Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Real Time RT-PCR02:57

Real Time RT-PCR

65.1K
Real-time reverse transcription-polymerase chain reaction, or Real-time RT-PCR, is an analytical tool used to determine the expression level of target genes. The method involves converting mRNA to complementary DNA with the help of an enzyme known as reverse transcriptase, followed by the PCR amplification of the cDNA. These two processes can be performed simultaneously in a single tube or separately as a two-step reaction.
The real-time quantification of the number of amplified products is...
65.1K
The Sense of Self: Reflected Self-Appraisal and Social Comparison02:57

The Sense of Self: Reflected Self-Appraisal and Social Comparison

56.1K
According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
56.1K
Angular Momentum01:21

Angular Momentum

819
Angular momentum characterizes an object's rotational motion and is defined as the moment of its linear momentum about a specified point O. When a particle moves along a curved path in the x-y plane, the scalar formulation calculates the magnitude of its angular momentum, utilizing the moment arm (d), representing the perpendicular distance from point O to the line of action of the linear momentum. Despite being scalar in formulation, angular momentum is inherently a vector quantity. Its...
819
Angular Velocity and Displacement01:08

Angular Velocity and Displacement

22.9K
Uniform circular motion is motion in a circle at a constant speed. Although this is the simplest case of rotational motion, it is very useful for many situations and is used to introduce rotational variables. When a particle is moving in a circle, the coordinate system is fixed and serves as a frame of reference to define the particle’s position. Its position vector from the origin of the circle to the particle sweeps out the angle θ, which increases in the counterclockwise direction...
22.9K
Conservation of Angular Momentum01:09

Conservation of Angular Momentum

16.2K
A system's total angular momentum remains constant if the net external torque acting on the system is zero. Considering a system that consists of n tiny particles, the angular momentum of any tiny particle may change, but the system's total angular momentum would remain constant. The principle of conservation of angular momentum only considers the net external torque acting on the system. While there are internal forces exerted by different particles within the system that also produce...
16.2K
Ion Channels01:19

Ion Channels

91.4K
The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
91.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nickel-Catalyzed 1,2-Distyrylation of 3-Buten-1-ol.

Organic letters·2026
Same author

Nickel-Catalyzed 1,2-Arylalkenylation of Unactivated Alkenes Enabled by a Native Hydroxy Group.

Angewandte Chemie (International ed. in English)·2026
Same author

Carrier-Dynamics-Regulated BiOI/Au/TiO<sub>2</sub> Z-Scheme Photoanode for Selective Glycerol Photoelectrooxidation and Mass-Transfer-Enhanced Continuous-Flow Operation.

Angewandte Chemie (International ed. in English)·2026
Same author

Closed-loop high-precision two-photon lithography based on a multiplexed single-cavity dual-comb laser.

Nature communications·2026
Same author

Model-Driven Deep Learning Enables Speckle-Free Holography for 3D Parallel Nanofabrication.

Research (Washington, D.C.)·2026
Same author

Recent Advances in Photoinduced Iron Catalysis for Decarboxylative C-Heteroatom Bonds Formation.

Chemical record (New York, N.Y.)·2026

Related Experiment Video

Updated: Feb 2, 2026

Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance SPR
09:35

Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance SPR

Published on: November 29, 2014

23.5K

Real-time multi-channel SPR sensing based on DMD-enabled angular interrogation.

Dongping Wang, Fong-Chuen Loo, Hengji Cong

    Optics Express
    |November 25, 2018
    PubMed
    Summary
    This summary is machine-generated.

    A novel digital micro-mirror device (DMD) biosensing system enables real-time surface plasmon resonance (SPR) measurements. This advanced SPR biosensor offers high resolution and a low detection limit for biomolecular interactions.

    More Related Videos

    Author Spotlight: Microfluidic Channel-Based Soft Electrodes and Their Application in Capacitive Pressure Sensing
    05:57

    Author Spotlight: Microfluidic Channel-Based Soft Electrodes and Their Application in Capacitive Pressure Sensing

    Published on: March 17, 2023

    4.2K
    Microfluidic Chip for Axonal Injury Models Construction and Enabling Multi-Omics Analysis
    11:00

    Microfluidic Chip for Axonal Injury Models Construction and Enabling Multi-Omics Analysis

    Published on: October 14, 2025

    1.2K

    Related Experiment Videos

    Last Updated: Feb 2, 2026

    Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance SPR
    09:35

    Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance SPR

    Published on: November 29, 2014

    23.5K
    Author Spotlight: Microfluidic Channel-Based Soft Electrodes and Their Application in Capacitive Pressure Sensing
    05:57

    Author Spotlight: Microfluidic Channel-Based Soft Electrodes and Their Application in Capacitive Pressure Sensing

    Published on: March 17, 2023

    4.2K
    Microfluidic Chip for Axonal Injury Models Construction and Enabling Multi-Omics Analysis
    11:00

    Microfluidic Chip for Axonal Injury Models Construction and Enabling Multi-Omics Analysis

    Published on: October 14, 2025

    1.2K

    Area of Science:

    • Biophotonics and Biosensing
    • Surface Plasmon Resonance (SPR) Technology
    • Digital Micro-mirror Device (DMD) Applications

    Background:

    • Surface Plasmon Resonance (SPR) is a label-free optical technique widely used for detecting biomolecular interactions.
    • Traditional SPR systems often require complex optical setups and can be limited in terms of speed and multi-channel capabilities.
    • The integration of Digital Micro-mirror Devices (DMDs) offers potential for novel optical interrogation methods.

    Purpose of the Study:

    • To develop and demonstrate a real-time, multi-channel biosensing system utilizing a DMD for angular interrogation SPR.
    • To evaluate the performance of the DMD-enabled SPR system in detecting biomolecular binding events.
    • To establish a new design for practical, solid-state SPR biosensing with enhanced features.

    Main Methods:

    • A digital micro-mirror device (DMD) was employed to achieve angular scanning for SPR measurements.
    • A single-point photodetector was used in conjunction with the DMD for SPR signal acquisition.
    • A four-channel measurement setup was implemented for simultaneous real-time monitoring.

    Main Results:

    • Real-time monitoring of bovine serum albumin (BSA) and anti-BSA binding interactions was successfully performed.
    • The system demonstrated a high resolution of 3.54 × 10-6 refractive index units (RIU).
    • A low detection limit of 9 ng/mL was achieved for the analyzed biomolecular interactions.

    Conclusions:

    • The developed DMD-based SPR system provides a novel and practical approach for solid-state biosensing.
    • The system offers user-selectable interrogation ranges, improved signal-to-noise ratio, and fast data throughput.
    • This technology represents a significant advancement for real-time, multi-channel biosensing applications.