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Intravitreal Injections in the Ovine Eye
Published on: July 5, 2022
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[Evaluation of intravitreal injection practice patterns in Cotonou].
L Agbahoungba1, S Alamou2, C Abouki3
1Clinique Ophtalmologique la Lumière, Cotonou, Bénin; Centre d'Exploration de la Rétine, Cotonou, Bénin.
Journal Francais D'Ophtalmologie
|November 25, 2018
Summary
Intravitreal injections are a safe and effective treatment for posterior segment eye conditions like diabetic macular edema. Ocular hypertension is the main complication, often linked to triamcinolone use.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Pharmacology
Background:
- Intravitreal injections deliver high medication concentrations to the posterior segment of the eye.
- Assessing the safety and tolerability of intravitreal injections is crucial for patient care.
- Understanding indications and complications informs clinical practice and drug selection.
Purpose of the Study:
- To evaluate the safety and tolerability of intravitreal injections.
- To analyze the primary indications for intravitreal injections.
- To identify and analyze complications associated with intravitreal injections.
Main Methods:
- Retrospective analysis of consecutive patients receiving intravitreal injections from January 2015 to June 2016.
- Inclusion of all patients with a complete ophthalmologic work-up before and follow-up at 1 week and 1 month post-injection.
- Safety measured by incidents or accidents during the injection procedure.
Main Results:
- 124 intravitreal injections were safely administered to 49 patients.
- Primary indications included diabetic macular edema (53.06%) and vein occlusion-related macular edema (26.53%).
- Ocular hypertension (60%) was the most frequent complication, primarily associated with triamcinolone; Ranibizumab was the most used drug (51.02%).
Conclusions:
- Intravitreal injection is a safe and feasible procedure in the studied context, achieving effective drug concentrations.
- Significant visual acuity improvements were observed, highlighting the benefits of intravitreal medication delivery.
- Challenges remain regarding the supply and preservation of anti-VEGF drugs, impacting accessibility.
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