Related Experiment Video
Updated: Feb 2, 2026

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels
Published on: May 26, 2023
Mitral valve repair versus replacement with preservation of the entire subvalvular apparatus
Eiri Kisamori1, Satoru Otani2, Tsuyoshi Yamamoto2
1Department of Cardiovascular Surgery, National Hospital Organization Iwakuni Clinical Center, 1-1-1 Atagocho, Iwakuni, Yamaguchi, 740-8510, Japan. e.kisamori@gmail.com.
Objective:
This study aimed to evaluate the outcomes of mitral valve (MV) repair versus MV replacement with preservation of the entire subvalvular apparatus.
Methods:
We retrospectively searched our dedicated in-hospital database for patients who underwent MV surgery between 2012 and 2017.
Results:
A total of 82 patients were divided into a group that underwent MV replacement (n = 35) and a group that underwent MV repair (n = 47). Patients undergoing MV replacement were significantly older (p < 0.01). Mortality at 30 days was not significantly different [MV replacement: n = 1 (2.9%), MV repair: n = 0 (0%); p = 0.43]. The single case of 30-day mortality after MV replacement was due to acute aortic dissection. The total cohort did not show significant differences in long-term survival (p = 0.07). There were no cardiac-related deaths in this cohort. Postoperative left ventricular end-diastolic diameter (MV replacement: 45.4 ± 6.2 mm, MV repair: 45.6 ± 5.8 mm; p = 0.89), left ventricular end-systolic diameter (MV replacement: 29.6 ± 7.1 mm, MV repair: 29.4 ± 5.2 mm; p = 0.89), and ejection fraction (MV replacement: 59.2 ± 11.4%, MV repair: 62.0 ± 6.8%; p = 0.17) were not significantly different.
Conclusions:
This study found that MV replacement had operative mortality, long-term survival, and complication rates similar to those of MV repair. There were no cardiac-related deaths in this cohort. MV replacement with preservation of the entire subvalvular apparatus does not seem to be inferior to MV repair.
Insights
Mitral valve (MV) replacement with subvalvular apparatus preservation showed similar operative mortality, long-term survival, and complication rates compared to MV repair. This approach is not inferior to traditional MV repair methods.
Area of Science:
- Cardiovascular Surgery
- Cardiac Valve Disease
- Surgical Outcomes
Background:
- Mitral valve (MV) disease is a significant cardiac condition requiring surgical intervention.
- Surgical options include mitral valve repair and mitral valve replacement.
- Preservation of the subvalvular apparatus during MV replacement is a technique that warrants outcome evaluation.
Purpose of the Study:
- To compare the clinical outcomes of mitral valve (MV) repair versus MV replacement with preservation of the entire subvalvular apparatus.
- To assess operative mortality, long-term survival, and complication rates between the two surgical techniques.
Main Methods:
- Retrospective analysis of patients undergoing MV surgery between 2012 and 2017.
- Division of patients into MV replacement (n=35) and MV repair (n=47) groups.
- Comparison of demographic data, mortality, long-term survival, and echocardiographic parameters.
Main Results:
- No significant difference in 30-day mortality (MV replacement: 2.9% vs. MV repair: 0%; p=0.43).
- Similar long-term survival rates between groups (p=0.07).
- No significant differences in postoperative left ventricular dimensions and ejection fraction between MV replacement and MV repair.
Conclusions:
- Mitral valve replacement with subvalvular apparatus preservation demonstrated comparable operative mortality and long-term survival to mitral valve repair.
- No cardiac-related deaths occurred in the study cohort.
- MV replacement with subvalvular apparatus preservation appears to be a viable alternative to MV repair.
Related Concept Videos
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Mitral Valve Prolapse III: Nursing Management
Golgi Apparatus
Golgi Apparatus
The Golgi apparatus is a eukaryotic organelle that has a distinctive ribbon-like appearance. It is a primary sorting and dispatch station for cargo arriving from the ER. Newly arriving vesicles enter the cis face of the Golgi, closest to the ER, and are...
Mismatch Repair

