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A Simple Approach to Induce Experimental Autoimmune Neuritis in C57BL/6 Mice for Functional and Neuropathological Assessments
Published on: November 9, 2017
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Diagnostic histochemistry in neuropathology.
1Division of Neuropathology, Department of Pathology, University of Virginia Medical Center, Charlottesville, VA, United States.
Seminars in Diagnostic Pathology
|November 26, 2018
Summary
Histochemistry is crucial for diagnosing neurological diseases by identifying neural and glial cells. This review covers essential stains and rapid methods for neuropathology, including lectin-histochemistry.
Area of Science:
- Neuropathology
- Histochemistry
- Neuroscience
Background:
- Histochemistry has a long history in neuropathology.
- It is vital for characterizing and diagnosing neurological diseases.
Purpose of the Study:
- To review histochemical stains used in identifying neural and glial components.
- To discuss rapid intraoperative diagnostic methods.
- To explore the role of lectin-histochemistry in neuropathology.
Main Methods:
- Review of established histochemical staining techniques.
- Discussion of rapid smear methods for intraoperative assessment.
- Exploration of lectin-histochemistry applications.
Main Results:
- Histochemistry enables identification of neurons, axons, myelin, and glial cells.
- Rapid methods facilitate intraoperative neuropathological diagnosis.
- Lectin-histochemistry shows potential in diagnostic neuropathology.
Conclusions:
- Histochemical stains are indispensable tools in diagnostic neuropathology.
- Rapid techniques enhance intraoperative diagnostic capabilities.
- Lectin-histochemistry offers a promising avenue for future diagnostic applications.
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