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Related Experiment Videos

Indomethacin-associated cholestasis.

M S Cappell1, O Kozicky, L S Competiello

  • 1Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461.

Journal of Clinical Gastroenterology
|August 1, 1988
PubMed
Summary

Indomethacin therapy can cause cholestasis, a liver injury characterized by elevated alkaline phosphatase. This condition resolved after discontinuing the drug, with no other cause found.

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Area of Science:

  • Hepatology
  • Pharmacology
  • Internal Medicine

Background:

  • Indomethacin is a widely used nonsteroidal anti-inflammatory drug (NSAID).
  • Drug-induced liver injury (DILI) is a significant concern in clinical practice.
  • Hepatic injury associated with indomethacin is rare, with few documented cases.