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Related Concept Videos

Additional Routes of Drug Administration01:18

Additional Routes of Drug Administration

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Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent properties of the drug being used.
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Routes of Drug Administration: Enteral01:18

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Medications can be administered through the enteral route using liquids, capsules, or tablets.
Enteral administration involves drug administration via the mouth in two ways: orally or sublingually.
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The administration of drugs via parenteral routes allows for direct drug introduction into the systemic circulation, resulting in high bioavailability because the medication bypasses the harsh conditions of the gastrointestinal tract and hepatic metabolism.
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Routes of Drug Administration: Overview01:22

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Drug administration involves delivering drugs to the body through various routes, such as enteral, parenteral, and topical.
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Two-Compartment Open Model: Extravascular Administration01:12

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The two-compartment model for extravascular administration represents a drug's absorption and distribution process. It features a central compartment, where the drug is first absorbed, and a peripheral compartment, which illustrates the drug's distribution throughout the body. The rate of change in drug concentration in the central compartment is calculated by three exponents: absorption, distribution, and elimination.
The absorption exponent (ka) indicates the speed at which the drug...
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Drug Administration and Therapy Phases: Overview01:26

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Drugs, the chemical agents used in diagnosing, treating, or preventing diseases, undergo a four-phase process of development: pharmaceutic, pharmacokinetics, pharmacodynamics, and therapeutic.
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The ITS2 Database
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The ITS2 Database

Published on: March 12, 2012

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Administrative databases.

Calista M Harbaugh1, Jennifer N Cooper2

  • 1Department of Surgery, University of Michigan Medical School, Ann Arbor, MI, USA.

Seminars in Pediatric Surgery
|November 27, 2018
PubMed
Summary
This summary is machine-generated.

Selecting administrative healthcare databases for research requires careful consideration of the specific research question. Different databases offer varying strengths and limitations for analyzing patient data, costs, and resource utilization.

Keywords:
Administrative dataHealth services researchPediatric surgery

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Area of Science:

  • Health Services Research
  • Medical Informatics
  • Pediatric Surgery

Background:

  • Administrative healthcare databases compile service utilization and payment records for billing.
  • These databases contain extensive patient data, including diagnoses, procedures, resource use, and costs.
  • Significant variability exists in patient populations and data elements across different databases.

Purpose of the Study:

  • To guide researchers in selecting appropriate administrative healthcare databases.
  • To highlight key considerations for matching databases to specific research questions.
  • To describe common administrative databases used in pediatric surgical research.

Main Methods:

  • Review of administrative healthcare database characteristics.
  • Discussion of factors influencing database selection for research.
  • Identification of databases frequently utilized in pediatric surgical studies.

Main Results:

  • Database selection must align with the specific research question.
  • Understanding each database's strengths, limitations, and data elements is crucial.
  • Several administrative databases are commonly employed for pediatric surgical research.

Conclusions:

  • Careful selection of administrative healthcare databases is essential for robust research.
  • Researchers must critically evaluate database characteristics in relation to their study objectives.
  • This review provides a framework for choosing suitable databases for pediatric surgical research.