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Updated: Feb 2, 2026

Triplet Fusion Upconversion Nanocapsule Synthesis
Published on: September 7, 2022
An ultrathin iron-porphyrin based nanocapsule with high peroxidase-like activity for highly sensitive glucose
Xiaotong Fan1, Ruizhen Tian, Tingting Wang
1State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, 2699 Qianjin Road, Changchun 130012, China. junqiuliu@jlu.edu.cn.
Abstract:
For the first time, an ultrathin iron-porphyrin based polymer nanocapsule with multiple peroxidase-like catalytic centers was constructed by covalently assembling iron-porphyrin monomers; this nanocapsule with a single molecule thickness shell acted as a highly efficient artificial enzyme for mimicking peroxidase. On the basis of the peroxidase-like activity of Fe-TPyP based nanocapsules (Fe-TPyP NCs), a highly sensitive colorimetric sensor for glucose determination was fabricated, the limit of detection was found to be as low as 0.098 μM. This study provided a novel strategy for developing artificial enzymes based on covalently assembled nanostructures. Furthermore, the colorimetric sensor for glucose determination showed potential applications in biomedicine and biology.
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