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Sonographic assessment of normal renal size in children with myelodysplasia

G W Gross1, D K Boal

  • 1Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107.

The Journal of Urology
|October 1, 1988
PubMed

Insights

This study establishes a normal renal growth curve for children with spina bifida using ultrasound measurements. Renal size in these children is generally smaller than in healthy peers.

Area of Science:

  • Pediatric Urology
  • Medical Imaging
  • Developmental Biology

Background:

  • Regular monitoring of upper urinary tract anatomy and kidney size is crucial for managing pediatric myelodysplasia (spina bifida).
  • Previous research utilized excretory urography to assess renal growth in this population.
  • Ultrasonography offers a non-invasive method for evaluating renal parameters.

Purpose of the Study:

  • To evaluate renal size and growth patterns in children with spina bifida using ultrasonography.
  • To compare renal measurements in spina bifida patients to those of normal children.
  • To develop a normative renal growth curve for pediatric spina bifida patients.

Main Methods:

  • Analysis of 297 renal ultrasonographic examinations from 145 pediatric patients with spina bifida.
  • Exclusion of patients with vesicoureteral reflux (grade ≥2), congenital renal anomalies, hydronephrosis, renal scarring, or prior urinary tract surgery.
  • Calculation of mean renal length and standard deviations based on sonographic measurements.

Main Results:

  • Mean renal length for each age group in spina bifida patients was generally below the mean values observed in normal children.
  • Sonographic measurements provided data for establishing age-specific renal size parameters.
  • A distinct growth pattern was observed compared to typical renal development.

Conclusions:

  • A normative renal growth curve, based on sonographic measurements, has been developed for clinical application in children with spina bifida.
  • This curve aids in the urological management and monitoring of renal development in this patient group.
  • The findings highlight potential differences in renal growth trajectories for children with spina bifida.

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