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Updated: Feb 2, 2026

The Tail Suspension Test
Published on: January 28, 2012
1H, 15N, 13C resonance assignment of the human CD44 cytoplasmic tail (669-742)
Benjamin Frühbauer1, Borja Mateos1, Robert Konrat2
1Max F. Perutz Laboratories, Department of Computational and Structural Biology, University of Vienna, Campus Vienna Biocenter 5, 1030, Vienna, Austria.
Abstract:
CD44 is a universally and abundantly expressed single-pass type I protein that spans the cytoplasmic membrane and is considered the principal receptor for hyaluronan in the extracellular matrix. CD44 exerts a multitude of biological functions, especially in cell adhesion and migration, and its deregulation has several pathological implications, including a putative role in cancer cell dissemination. Here we report the NMR chemical shift assignment of the recombinant intrinsically disordered CD44 cytoplasmic region (669-742).
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