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Updated: Feb 2, 2026

Preparation of Binary and Ternary Deep Eutectic Systems
Published on: October 31, 2019
Dynamic Nuclear Polarization using Photoexcited Triplet Electron Spins in Eutectic Mixtures
Akinori Kagawa1,2,3, Makoto Negoro1,2,3, Ryohei Ohba1
1Graduate School of Engineering Science , Osaka University , Toyonaka , Osaka 560-8531 , Japan.
Abstract:
Dynamic nuclear polarization using photoexcited triplet electrons (Triplet-DNP) is a method to significantly enhance nuclear spin polarization even in a low magnetic field and at room temperature. Pentacene has been practically used as an efficient polarizing agent for Triplet-DNP. In this study, we demonstrate room temperature 1H and 13C hyperpolarization of eutectic mixtures of deuterated benzoic acid doped with pentacene and a target molecule such as salicylic acid, nicotinic acid, or 2-naphthoic acid. These molecules are otherwise difficult to hyperpolarize by Triplet-DNP due to the low pentacene dopabilities of these molecules. The highest 1H polarization of 1.2% has been obtained for the eutectic mixture of salicylic acid in 0.39 T. The present sample preparation is a crucial method to widen the range of applications of Triplet-DNP to chemical and biomedical analyses.
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