Related Experiment Video
Updated: Feb 2, 2026

10:33
Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
Published on: August 14, 2019
9.0K
The NIH BRAIN Initiative: Advancing neurotechnologies, integrating disciplines
Meghan C Mott1, Joshua A Gordon2, Walter J Koroshetz1
1National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America.
Plos Biology
|November 27, 2018
Summary
The National Institutes of Health
Area of Science:
- Neuroscience
- Biotechnology
- Medical Research
Background:
- The National Institutes of Health (NIH) launched the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative in 2014.
- This 10-year program aims to revolutionize understanding of the human brain's information processing.
- The initiative focuses on developing and applying cutting-edge neurotechnologies.
Purpose of the Study:
- To review the progress of the BRAIN Initiative.
- To outline the future trajectory of BRAIN Initiative research.
- To assess advancements in understanding brain circuits.
Main Methods:
- Review of research progress and future plans within the BRAIN Initiative.
- Analysis of the development and application of innovative neurotechnologies.
- Evaluation of the impact on understanding brain circuit function.
Main Results:
- Significant advancements have been made in neurotechnology development.
- Progress is being achieved in mapping and understanding brain circuits.
- The initiative is on track to meet its 10-year goals.
Conclusions:
- The BRAIN Initiative is successfully driving innovation in neuroscience.
- Continued development and application of neurotechnologies are crucial.
- The program is poised to significantly enhance our understanding of the brain.
Related Concept Videos
Initiation of Translation
39.0K
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
39.0K
Initiation of Translation
8.1K
8.1K
Transcription Initiation
21.0K
Initiation is the first step of transcription in eukaryotes. Prokaryotic RNA Polymerase (RNAP) can bind to the template DNA and start transcribing. On the other hand, transcription in eukaryotes requires additional proteins, called transcription factors, to first bind to the promoter region in the DNA template. This binding helps recruit the specific RNAP that can assemble on the DNA and start transcription.
The promoters and enhancers and their accessory proteins allow tight regulation of...
The promoters and enhancers and their accessory proteins allow tight regulation of...
21.0K
Integration by Parts: Indefinite Integrals
173
Integration by parts is a fundamental technique in calculus for evaluating integrals involving the product of two functions. It is particularly useful when direct integration is not feasible. The method is based on the product rule for differentiation, which states that the derivative of a product equals the derivative of the first function times the second, plus the first function times the derivative of the second. By integrating this identity and rearranging terms, the integration by parts...
173
Integration by Parts: Definite Integrals
80
Definite integrals involving the product of two functions over a fixed interval can be evaluated using integration by parts. This method rewrites the integral as the difference of a product evaluated at the endpoints and a remaining definite integral that is often simpler to compute.A representative example is the definite integral of the inverse tangent function. Since there is no direct integration formula for arctan x, the integrand is rewritten as a product of arctan x and the...
80
S-Cdk Initiates DNA Replication
5.7K
The cell cycle is a series of events leading to DNA duplication followed by the division of cell content to form two daughter cells. The cell cycle progresses in four stages—the cell increases in size (gap 1 or G1-phase), duplicates its DNA (synthesis or S-phase), prepares to divide (gap 2 or G2-phase), and divides (mitosis or M-phase).
Two states at the origin of replication
In eukaryotes, the initiation of replication occurs at many sites on the chromosomes, called the origins of...
Two states at the origin of replication
In eukaryotes, the initiation of replication occurs at many sites on the chromosomes, called the origins of...
5.7K

