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Author Spotlight: Non-Surgical Treatment of Melasma– Microneedling with Tranexamic Acid
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Melasma: update on management

Amanda K Suggs1, Selina S Hamill2, Paul M Friedman2,3,4

  • 1Dermatology and Laser Surgery Center, Houston, Texas, USA. drsuggs@dermlasersurgery.com.

Seminars in Cutaneous Medicine and Surgery
|November 27, 2018
PubMed

Insights

Melasma treatment requires reducing pigment production and increasing its elimination. A combination approach, including topical inhibitors, peels, and lasers, is key for managing this common skin pigment disorder.

Area of Science:

  • Dermatology
  • Cosmetic Science

Background:

  • Melasma is a prevalent, acquired, chronic skin condition characterized by hyperpigmentation.
  • It presents significant treatment challenges due to its persistent nature and high likelihood of recurrence.

Purpose of the Study:

  • To outline a comprehensive treatment strategy for melasma.
  • To emphasize the necessity of a multimodality approach for achieving disease remission and equilibrium.

Main Methods:

  • Utilizing topical tyrosinase inhibitors to reduce melanin synthesis.
  • Employing peels and laser/light-based devices to enhance melanin elimination.
  • Implementing strict photoprotection measures to prevent recurrence and hyperpigmentation.

Main Results:

  • A combination therapy targeting both pigment production and elimination is essential for effective melasma management.
  • Maintenance therapies are frequently required to sustain remission.
  • Addressing vascular components through treatments like pulsed dye laser or tranexamic acid offers an additional therapeutic avenue.

Conclusions:

  • Effective melasma management necessitates a multifaceted strategy combining pigment reduction, enhanced elimination, and vigilant photoprotection.
  • Long-term maintenance and addressing vascular factors are crucial for sustained control of this recurrent condition.

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