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Updated: Feb 2, 2026

Acute Myocardial Infarction in Rats
Published on: February 16, 2011
Case report: Apical variant hypertrophic cardiomyopathy simulating an acute inferior myocardial infarction
Juan Morales1, Miller Giraldo2
1Universidad del Valle, School of Medicine, Cali, Colombia.
Insights
A patient presenting with chest pain was diagnosed with apical variant hypertrophic cardiomyopathy or Yamaguchi syndrome after initial tests for acute myocardial infarction were negative. This highlights the importance of considering rare cardiac conditions in chest pain evaluations.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Chest pain is a common presenting complaint in emergency departments.
- Acute myocardial infarction is a primary concern in patients with cardiac risk factors and suggestive electrocardiographic findings.
Observation:
- A female patient presented with chest pain and no prior medical history.
- Electrocardiographic findings and risk factors prompted suspicion of acute myocardial infarction.
Findings:
- Coronary catheterization and subsequent studies ruled out coronary artery disease.
- Further investigations confirmed apical variant hypertrophic cardiomyopathy or Yamaguchi syndrome.
Implications:
- This case underscores the need for a broad differential diagnosis in patients with chest pain.
- Recognizing rare cardiomyopathies like apical variant hypertrophic cardiomyopathy is crucial for accurate diagnosis and management.
Abstract:
We present a female patient who arrived to the emergency department with chest pain without known medical history at the time of consultation. Considering her risk factors and electrocardiographic findings, it was decided to perform a coronary catheterization under the suspicion of acute myocardial infarction. The catheterization and another studies was negative for coronary artery disease. Additional studies were conclusive for apical variant hypertrophic cardiomyopathy or Yamaguchi syndrome.
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